18 results
diagnosis hematology management differential classification leukemia mds myelodysplastic pain vasculitis algorithm anemia aplastic apml approach arthritis chronic cll conditions cppd
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
reactive arthritis, gout ... Send for cell count ... Parallel, yellow = gout ... #rheumatology # ... approach #workup
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
microglobulin Treatment ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... = funny-shaped cells ... Allogeneic stem cell ... only curative treatment ... #hematology #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... anemia DDX: Rule Out ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
neuritis - Giant cell ... Nodules • RA • Gout ... Tophi - Gout ... pulses - Giant cell ... differential #diagnosis #rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
bone pain, fever, joint ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
SAPHO Syndrome Summary ... SAPHO syndrome is ... diagnosis • Rule out ... and lower jaw Treatment ... #Rheumatology #
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
swelling in weird joints ... MCP, or shoulder joints ... deposition in joints ... • Metabolic syndrome ... #Comparison #rheumatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Release from blast cells ... • Induce blast cell ... #oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
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