Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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management diagnosis druginduced erythematosus systemic comparison dil hemophagocytic hlh lymphohistiocytosis nephritis nephrology table
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
and Management Summary ... life-threatening • Treatment ... • Evolution: ... Diagnosis #Management #Summary ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... - Summary Antinuclear ... severe disease Treatment ... #Systemic #Lupus ... #rheumatology #
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... cutaneous-DIL • Evolution ... life-threatening • Treatment ... • Evolution: ... #table #rheumatology
Management of Lupus Nephritis Lupus nephritis (LN) in 10 to 40% of SLE Hallmark = proteinuria 20.5 g/g
Nephritis Lupus ... in 10 to 40% of SLE ... renal histological evaluation ... Nephritis #Management #treatment ... #management #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... Unknown cause Treatment ... inhibitors under evaluation ... diagnosis #management #treatment ... #summary #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
is rare in DIL, SCLE-DIL ... constitutional symptoms • Treatment ... cutaneous-DIL • Evolution ... #DIL #rheumatology ... #diagnosis #treatment
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