Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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differential associations causes rheumatology anemia autoantibodies coagulation connectivetissuediseases ctild deficiencies deficiency diseases extravascular hemolysis hemolytic hepatorenal hrs hrsaki hrsckd hrsnaki
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... #hematology #anemia
Hyponatremia - Differential Diagnosis by Mechanism Decr Blood Pressure (“Decr Effective Circulating Volume”) - Volume depletion
- Cirrhosis Syndrome ... - Malignancy (e.g ... CNS pathology (e.g ... pathology (e.g. ... #Table #Causes
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g ... warfarin, DOACs (e.g ... Autoimmune disorders (e.g ... #comparison #diagnosis ... #hematology #deficiency
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- Vasculitis, e.g ... - Vasculitis, e.g ... Associations #diseases #diagnosis ... #table #rheumatology ... #antibodies
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
PSS: Sjogren syndrome ... LungDisease #CTILD #Diagnosis ... #Differential #Comparison ... #Table #Pulmonary ... #Rheumatology #
Hepatorenal Syndrome (HRS) - Diagnostic Criteria HRS-AKI (Acute: previously known as HRS Type 1) • ↑ Creatinine
Hepatorenal Syndrome ... (HRS) - Diagnostic ... Criteria HRS-AKI ... nephrotoxics (e.g ... #HRSNAKI #hepatology
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
: ARDS Berlin Criteria ... , and CXR with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison ... #table
Hyperthermic Toxidromes Five toxidromes may present with overlapping features: hyperthermia, rhabdomyolysis, altered mental status/seizures. • Sympathomimetic -
• Serotonin Syndrome ... dopamine blockers (e.g ... dopamine agonists (e.g ... Hyperthermic #Toxidromes #comparison ... #table #diagnosis
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