Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Hypocalcemia - Workup Algorithm

Dr Nikhil Lohiya - NEPHKIDS 2020 @NEPHKIDS1

#Hypocalcemia #Workup #Algorithm #differential #diagnosis #endocrinology #causes
Hypocalcemia - Workup ... #Workup #Algorithm ... #differential # ... diagnosis #endocrinology ... #causes #calcium
Hypercalcemia Workup and Differential Diagnosis Framework
1) Determine whether PTH-dependent
2) Assess for other hormonal causes
3) Assess for
Hypercalcemia Workup ... and Differential ... #Workup #Differential ... #Diagnosis #algorithm ... #endocrinology
Causes of Hypercalcemia - Differential Diagnosis Algorithm
 • Primary Hyperparathyroidism 
 • Possible Familial Hypocalciuric Hypercalcemia
Causes of Hypercalcemia ... - Differential ... Diagnosis Algorithm ... Diagnosis #Algorithm ... #Causes #endocrinology
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
Differential Diagnosis ... Algorithm Elevated ... #Differential # ... Diagnosis #Algorithm ... #causes #endocrinology
Reflex Testing - Causes of Hyporeflexia and Hyperreflexia
Focal Hyporeflexia: 
 • Radiculopathy, Mononeuropathy, Polyneuropathy, Acute stroke,
Hyporeflexia: • Hypercalcemia ... polyneuropathy (e.g ... Hyperreflexia: • Hypocalcemia ... #differential # ... diagnosis #table
Gynecomastia - Differential Diagnosis a
nd Workup Algorithm
Gynecomastia is common in clinical practice, affecting ~50% of males
Diagnosis a nd ... Workup Algorithm ... Labs: TSH, Cr, LFTs ... #Diagnosis #Workup ... #Algorithm #endocrinology
Hypercalcemia Evaluation
1) Clinical clues
 - Is the patient symptomatic?
 - Family history?
 - Have you done
Hypercalcemia Evaluation ... 1) Clinical clues ... #workup #differential ... #diagnosis #endocrinology ... elevated #evaluation #workup
Causes of Hypercalcemia
Parathyroid hormone–dependent
Primary hyperparathyroidism
Familial hypocalciuric hypercalcemia
Lithium-associated
Tertiary hyperparathyroidism
Genetic disorders (e.g., multiple endocrine neoplasia type 1 or
Causes of Hypercalcemia ... hypocalciuric hypercalcemia ... Genetic disorders (e.g ... #Causes #Differential ... #Diagnosis #Endocrinology
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Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Diagnosis Algorithm ... Weakness, fatigue, nausea ... hyponatremia, hyperkalemia ... #Diagnosis #Algorithm ... #endocrinology
Etiologies of Hypernatremia - Differential Diagnosis
GI losses / Insensible losses
Sodium Overload
Transcellular Movement of Water
Central Diabetes Insipidus
Hypernatremia - Differential ... Diagnosis GI losses ... cisplatin) - Chronic hypercalcemia ... #Diagnosis #Table ... #Causes