Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 β€’ Defect in fetal free fatty acid metabolism products β†’
of Pregnancy (AFLP ... = nonspecific (nausea ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... Pregnancy #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 β€’ Infectious: Hepatitis C, A,
Causes of Acute ... Liver Injury - Differential ... #Injury #Differential ... #Diagnosis #Causes ... Acute #algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 β€’ NAFLD
 β€’ Cirrhosis
 β€’
Tests (LFTs) - Differential ... Chronic Viral Hepatitis ... β€’ Acute Viral Hepatitis ... #Tests #LFTs #Differential ... #Diagnosis #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... (ALT or AST > ALP ... Wilsons, Pregnancy - AFLP ... Algorithm #diagnosis #hepatology
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... of Pregnancy (AFLP ... child * Severe cases ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... , Toxic Hepatitis ... #Patterns #Liver ... #Injury #hepatology ... transaminitis #differential
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 β€’ Onset/Trimester: 25-32 weeks
 β€’ Typical clinical features:
of Pregnancy (AFLP ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential ... diagnosis #icp #HELLP #AFLP
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (Β± cirrhosis)
Acute-on-Chronic Liver ... months without treatment ... Alcohol-Associated Hepatitis ... (DILI) Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Hepatic Masses on CT - Differential Diagnosis by CT Findings

Masses: Hemangioma, Adenoma, FNH, HCC, Fibrolamellar HCC,
Hepatic Masses on ... CT - Differential ... #CT #CTA #differential ... #diagnosis #liver ... #hepatology #radiology
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 β€’ Fever, acute onset RUQ pain,
Supportive with treatment ... progressing to acute liver ... Liver transplant ... Hepatobiliary #hepatology ... #hepatitis #differential