Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Digoxin Pharmacology and Monitoring

 β€’ Digoxin’s half-life is 30-45 hours in healthy adults
 β€’ When monitoring
Digoxin Pharmacology ... and Monitoring ... #Pharmacology # ... Monitoring #toxicology ... #management #toxicity
Utilization of Antibiotics as Antidotes

Valproic Acid Toxicity:
Carbapenems 

Amatoxin Mushrooms: 
Polymyxin B, Penicillin, Cyclosporine

Infographic by Mike O'Brien
@MikeEMPharmD

#Antibiotics
Utilization of Antibiotics ... Valproic Acid Toxicity ... MikeEMPharmD #Antibiotics ... #Antidotes #Toxicology ... #Pharmacology
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
Therapeutic Drug Level Monitoring ... at anytime if toxicity ... post dose (C2) Digoxin ... Therapeutic #Ranges #Toxicology ... #Pharmacology #
Flutycosine - Antibiotics Class Overview
 - 
Mechanism: 5-FC interferes with DNA and protein synthesis.  Only
Flutycosine - Antibiotics ... B for initial management ... monitored to reduce toxicity ... #Pharmacology #Antibiotics ... #Review #Overview
Antifungal Azoles - Antibiotics Class Overview

Mechanism:  inhibit ergosterol synthesis (important component of fungal cell membranes)
Antifungal Azoles - Antibiotics ... hepatic, main toxicity ... Isavuconazole(PO or IV) #Pharmacology ... #Antibiotics #Review
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
treatment for severe toxicity ... life-threatening toxicity ... #ILE #Therapy #Toxicology ... #Management #Pharmacology
Gamma hydroxybutyrate (GHB) - Toxicology

Clinical presentation
 - Symptoms of GHB toxicity include: short term anterograde amnesia,
hydroxybutyrate (GHB) - Toxicology ... Symptoms of GHB toxicity ... Hydroxybutyrate #GHB #Toxicology ... #Toxicity #Diagnosis ... #Management #Pharmacology
Rifampin Drug Interactions and Monitoring
Rifampin Drug Interactions of Major Clinical Significance:
Oral anticoagulants, Oral contraceptives, Cyclosporine, Digitoxin,
Interactions and Monitoring ... Cyclosporine, Digitoxin ... Dapsone, Diazepam, Digoxin ... #Interactions #pharmacology ... #management #monitoring
Oral Antibiotics for Acne - Indicated for Moderate-to-Severe Acne 
First-Line Drug Class: Tetracyclines 

In the last
Oral Antibiotics ... the last post I reviewed ... talk about oral antibiotics ... #Pharmacology # ... Management #Dermatology
Salicylate Poisoning - Toxicology

Acute toxicity = vomiting, tachypnea, tinnitus, diaphoresis, and lethargy. This may progress to
Salicylate Poisoning - Toxicology ... Acute toxicity ... Chronic toxicity ... #Toxicology #Pharmacology ... #Diagnosis #Management