Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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18 results
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... Diagnosis of MALA ... LacticAcidosis #Toxicity #Toxicology ... #Diagnosis #Management
Potassium Channel Blockers - Medications
1. Cardiovascular Drugs
2. Psychiatric drugs
3. Other drugs
4. Synthetic opioids: Levomethadyl 
5. Opium
Channel Blockers - Medications ... ChannelBlockers #Medications ... #Differential #Diagnosis ... #Pharmacology # ... Toxicology
Serotonin Syndrome Drug Precipitants and Pharmacology
↑ Serotonin Formation: Tryptophan, Oxitriptan
↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine
↑ Serotonin
Precipitants and Pharmacology ... Lithium ↓ Serotonin Metabolism ... Serotonin #Syndrome #Pharmacology ... #medications #causes ... #differential #diagnosis
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
widening #ECG #EKG #Pharmacology ... #Medications #Toxicology ... #Diagnosis #Differential
Uric Acid Homeostasis
In the liver, purines are metabolized to uric acid. The last step in purine
step in purine metabolism ... Homeostasis #Gout #Pathophysiology ... #Pharmacology # ... Medications #Management
Mechanisms of Drug-Induced Hyperkalemia 
 β€’ Direct renin inhibitor (Aliskiren)
 β€’ Renin release inhibition (NSAIDs, Beta-Blockers)
#differential #diagnosis ... #pathophysiology ... #pharmacology # ... potassium #medications
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... - Metabolism - ... #Clozapine #Toxicology ... #Toxicity #Diagnosis ... #Pharmacology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
and decreased metabolism ... ileal conduit - Medications ... deficiency #Ammonia #Pathophysiology ... #Differential #Diagnosis
Tramadol - Toxicology
Due to different CYP-2D6 genotypes, people variably metabolize tramadol into its active metabolite, M1
This
Tramadol - Toxicology ... people variably metabolize ... #Tramadol #Toxicology ... #Toxicity #Diagnosis ... #Pharmacology
Euglycemic Diabetic Ketoacidosis (EuDKA)
SGLT2 Inhibitors
Increasing Indications
Significant Adverse Drug Effects
Definition of EuDKA
 β€’ Metabolic acidosis with pH
Inhibitors Increasing Indications ... Definition of EuDKA β€’ Metabolic ... level < 200 mg/dL Pathophysiology ... Ketoacidosis #EuDKA #diagnosis