Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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16 results
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Syndrome (PRIS) ... Diagnosis is ... Hyperlactatemia β€’ Metabolic ... #Pharmacology # ... Toxicity #Toxicology
Metformin Associated Lactic Acidosis (MALA) 

Pathophysiology of MALA
 - Metformin interferes with the activity of the
Acidosis (MALA) Pathophysiology ... use in cellular metabolism ... Diagnosis of MALA ... LacticAcidosis #Toxicity #Toxicology ... #Diagnosis #Management
Serotonin Syndrome Drug Precipitants and Pharmacology
↑ Serotonin Formation: Tryptophan, Oxitriptan
↑ Serotonin Release: Amphetamines, Cocaine, Mirtazapine
↑ Serotonin
Serotonin Syndrome ... Precipitants and Pharmacology ... Lithium ↓ Serotonin Metabolism ... #Pharmacology # ... #differential #diagnosis
Causes of Pericardial Effusion - Differential Diagnosis
Infectious:
 β€’ Viral: Enterovirus, Herpesvirus, Adenovirus, Parvovirus
 β€’ Bacterial: Mycobacterium
of Pericardial Effusion ... - Differential Diagnosis ... Disease, Behcet Syndrome ... Mesothelioma β€’ Metabolic ... #Differential #Diagnosis
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... Pathophysiology ... β†’ Hypokalemia Metabolic ... #Pathophysiology ... #nephrology #diagnosis
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
Theophylline - For i/v infusion ... - Continuous infusion ... Therapeutic #Ranges #Toxicology ... #Pharmacology # ... Diagnosis #Table
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
Clozapine Toxicology ... - Metabolism - ... #Clozapine #Toxicology ... #Toxicity #Diagnosis ... #Pharmacology
Imaging Patterns of Toxic and Metabolic Brain Disorders

Thalami, Mammillary Bodies and Tectum: Wernicke Encephalopathy
Dentate Nuclei: Metronidazole,
Patterns of Toxic and Metabolic ... Symmetric Restricted Diffusion ... MRI #Patterns #Toxicology ... #Metabolic #Brain ... #Differential #Diagnosis
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
Respiratory or Metabolic ... - Differential Diagnosis ... D-lactate (short bowel syndrome ... - Rapid saline infusion ... Interpretation #Diagnosis
Causes of Dyspnea - Differential Diagnosis Algorithm
Cardiac:
 β€’ Dysrhythmia
 β€’ Ischemia
 β€’ Cardiomyopathy
 β€’ Valvular disease
- Differential Diagnosis ... Superior vena cava syndrome ... Pleura: β€’ Pleural effusion ... hypoventilation β€’ Metabolic ... #Differential #Diagnosis