Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Acetaminophen Intoxication Algorithm

- Dr. Josh Farkas @PulmCrit

#Acetaminophen #Algorithm #Toxicology #Overdose #Algorithm #Management #APAP #Overdose #Tylenol
Acetaminophen Intoxication ... @PulmCrit #Acetaminophen ... #Algorithm #Toxicology ... #Overdose #Algorithm ... Management #APAP #Overdose
Glucagon: Bypassing Ξ²-Blockade

Glucagon pathophysiology and clinical applications in anaphylaxis and beta-blocker overdose

#Toxicology #Pharmacology #Pathophysiology #Glucagon #BetaBlocker
Ξ²-Blockade Glucagon pathophysiology ... and beta-blocker overdose ... #Toxicology # ... Pharmacology #Pathophysiology ... #BetaBlockade #Overdose
Acetaminophen metabolism and factors affecting toxicity. 
GSH = glutathione 

#Acetaminophen #APAP #metabolism #toxicity #Toxicology #Pathophysiology #Overdose
Acetaminophen metabolism ... glutathione #Acetaminophen ... metabolism #toxicity #Toxicology ... #Pathophysiology ... #Overdose
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
#ILE #Therapy #Toxicology ... #Management #Pharmacology ... #Overdose #intralipid
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
gets saturated in overdoses ... #Pathophys #Toxicology ... NAcetylCysteine #Acetaminophen
N-Acetylcysteine (NAC) restores hepatic glutathione!
Found to have 21-28% reduction in mortality for acetaminophen-induced hepatic failure
The earlier
concentration of acetaminophen ... concern for ANY overdose ... of acetaminophen ... ) #Diagnosis #Toxicology ... #Nomogram #Acetaminophen
Naloxone - Toxicology

Adult starting dose:
 - 0.4 mg IV/IM/IO/SQ for non-opioid dependent patients
 - 0.04 mg
Naloxone - Toxicology ... Naloxone #Narcan #Toxicology ... #Management #Pharmacology ... #Overdose
Fomepizole for Acetaminophen Toxicity

 β€’ In cases where fomepizole and NAC were administered together, evidence has
Fomepizole for Acetaminophen ... hour equivalent acetaminophen ... #Fomepizole #Acetaminophen ... #Toxicology #pharmacology
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
N2O can cause a syndrome ... #Pathophysiology ... #Toxicology #NitrousOxide
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion Syndrome ... Related #Infusion #Syndrome ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology