Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Acetaminophen Intoxication Algorithm

- Dr. Josh Farkas @PulmCrit

#Acetaminophen #Algorithm #Toxicology #Overdose #Algorithm #Management #APAP #Overdose #Tylenol
Acetaminophen #Algorithm #Toxicology ... #Overdose #Algorithm ... #Management #APAP ... #Overdose #Tylenol
Glucagon: Bypassing Ξ²-Blockade

Glucagon pathophysiology and clinical applications in anaphylaxis and beta-blocker overdose

#Toxicology #Pharmacology #Pathophysiology #Glucagon #BetaBlocker
Ξ²-Blockade Glucagon pathophysiology ... and beta-blocker overdose ... #Toxicology # ... Pharmacology #Pathophysiology ... #BetaBlockade #Overdose
Acetaminophen metabolism and factors affecting toxicity. 
GSH = glutathione 

#Acetaminophen #APAP #metabolism #toxicity #Toxicology #Pathophysiology #Overdose
Acetaminophen #APAP ... metabolism #toxicity #Toxicology ... #Pathophysiology ... #Overdose
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
non-toxic route of APAP ... gets saturated in overdoses ... #Pathophys #Toxicology ... #NAC #APAP #NAcetylCysteine
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
#ILE #Therapy #Toxicology ... #Management #Pharmacology ... #Overdose #intralipid
Naloxone - Toxicology

Adult starting dose:
 - 0.4 mg IV/IM/IO/SQ for non-opioid dependent patients
 - 0.04 mg
Naloxone - Toxicology ... Naloxone #Narcan #Toxicology ... #Management #Pharmacology ... #Overdose
N-Acetylcysteine (NAC) restores hepatic glutathione!
Found to have 21-28% reduction in mortality for acetaminophen-induced hepatic failure
The earlier
concern for ANY overdose ... ) #Diagnosis #Toxicology ... Acetaminophen #Toxicity #APAP
The Inhibited Pathway caused by N2O, leading to a decrease in the active form of Vitamin
N2O can cause a syndrome ... #Pathophysiology ... #Toxicology #NitrousOxide
Fomepizole for Acetaminophen Toxicity

 β€’ In cases where fomepizole and NAC were administered together, evidence has
recommended for massive APAP ... Acetaminophen #Toxicology ... #pharmacology #
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion Syndrome ... Related #Infusion #Syndrome ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology