Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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11 results
Acetaminophen metabolism and factors affecting toxicity. 
GSH = glutathione 

#Acetaminophen #APAP #metabolism #toxicity #Toxicology #Pathophysiology #Overdose
Acetaminophen metabolism ... factors affecting toxicity ... APAP #metabolism #toxicity ... #Toxicology #Pathophysiology ... #Overdose
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
treatment for severe toxicity ... life-threatening toxicity ... #Therapy #Toxicology ... #Management #Pharmacology ... #Overdose #intralipid
Glucagon: Bypassing Ξ²-Blockade

Glucagon pathophysiology and clinical applications in anaphylaxis and beta-blocker overdose

#Toxicology #Pharmacology #Pathophysiology #Glucagon #BetaBlocker
Ξ²-Blockade Glucagon pathophysiology ... and beta-blocker overdose ... #Toxicology # ... Pharmacology #Pathophysiology ... #BetaBlockade #Overdose
N-Acetylcysteine (NAC) restores hepatic glutathione!
Found to have 21-28% reduction in mortality for acetaminophen-induced hepatic failure
The earlier
concern for ANY overdose ... of acetaminophen ... ) #Diagnosis #Toxicology ... #Nomogram #Acetaminophen ... #Toxicity #APAP
N-Acetyl Cysteine (NAC) Therapy Mechanism of Action: The non-toxic route of APAP metabolism gets saturated in
gets saturated in overdoses ... #Pathophys #Toxicology ... NAcetylCysteine #Acetaminophen ... #Toxicity #emDocs
Fomepizole for Acetaminophen Toxicity

 β€’ In cases where fomepizole and NAC were administered together, evidence has
Fomepizole for Acetaminophen ... Toxicity β€’ ... hour equivalent acetaminophen ... #Fomepizole #Acetaminophen ... #Toxicology #pharmacology
Stages of Iron Toxicity

Iron overdose can cause an anion gap metabolic acidosis. Severe cases can lead
Stages of Iron Toxicity ... Iron overdose ... hrs Stage Ill ... #Stages #Iron #Toxicity ... #Toxicology #Diagnosis
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion Syndrome ... Related #Infusion #Syndrome ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
in critically ill ... Propofol infusion syndrome ... glycol (solvent) toxicity ... No pharmacologic ... (Haldol) - No pharmacologic
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
of Colchicine Toxicity ... Respiratory Distress Syndrome ... #Colchicine #Toxicity ... #Toxicology #Phases ... #Pharmacology #