Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
treatment for severe toxicity ... life-threatening toxicity ... #Therapy #Toxicology ... #Management #Pharmacology ... #Overdose #intralipid
Glucagon: Bypassing Ξ²-Blockade

Glucagon pathophysiology and clinical applications in anaphylaxis and beta-blocker overdose

#Toxicology #Pharmacology #Pathophysiology #Glucagon #BetaBlocker
Ξ²-Blockade Glucagon pathophysiology ... and beta-blocker overdose ... #Toxicology # ... Pharmacology #Pathophysiology ... #BetaBlockade #Overdose
Acetaminophen metabolism and factors affecting toxicity. 
GSH = glutathione 

#Acetaminophen #APAP #metabolism #toxicity #Toxicology #Pathophysiology #Overdose
factors affecting toxicity ... APAP #metabolism #toxicity ... #Toxicology #Pathophysiology ... #Overdose
Gamma hydroxybutyrate (GHB) - Toxicology

Clinical presentation
 - Symptoms of GHB toxicity include: short term anterograde amnesia,
hydroxybutyrate (GHB) - Toxicology ... Symptoms of GHB toxicity ... symptoms can include agitation ... #Toxicity #Diagnosis ... #Management #Pharmacology
Management of Serotonin Syndrome
Identify and stop all serotoninergic medications
 β€’ Avoid inadvertent Rx of serotoninergic meds
Management of Serotonin Syndrome ... serotoninergic meds (i.e ... Benzodiazepines for agitation ... ucsdim #Serotonin #Syndrome ... Management #treatment #toxicology
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Pain, Agitation, ... Propofol infusion syndrome ... glycol (solvent) toxicity ... No pharmacologic ... (Haldol) - No pharmacologic
Stages of Iron Toxicity

Iron overdose can cause an anion gap metabolic acidosis. Severe cases can lead
Stages of Iron Toxicity ... Iron overdose ... hrs Stage Ill ... #Stages #Iron #Toxicity ... #Toxicology #Diagnosis
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion Syndrome ... Related #Infusion #Syndrome ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
of Colchicine Toxicity ... Respiratory Distress Syndrome ... #Colchicine #Toxicity ... #Toxicology #Phases ... #Pharmacology #
Methotrexate Toxicology 

Intravenous leucovorin (folinic acid) treatment serves as a cofactor necessary for synthesis of thymidylate
Methotrexate Toxicology ... the most severe overdoses ... evidence of marrow toxicity ... #Toxicity #Management ... #Pharmacology