Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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11 results
Intravenous Lipid Emulsion (ILE) Therapy

ILE is a treatment for severe toxicity from local anesthetics. In addition,
treatment for severe toxicity ... life-threatening toxicity ... #Therapy #Toxicology ... #Management #Pharmacology ... #Overdose #intralipid
Glucagon: Bypassing Ξ²-Blockade

Glucagon pathophysiology and clinical applications in anaphylaxis and beta-blocker overdose

#Toxicology #Pharmacology #Pathophysiology #Glucagon #BetaBlocker
Ξ²-Blockade Glucagon pathophysiology ... and beta-blocker overdose ... #Toxicology # ... Pharmacology #Pathophysiology ... #BetaBlockade #Overdose
Acetaminophen metabolism and factors affecting toxicity. 
GSH = glutathione 

#Acetaminophen #APAP #metabolism #toxicity #Toxicology #Pathophysiology #Overdose
factors affecting toxicity ... APAP #metabolism #toxicity ... #Toxicology #Pathophysiology ... #Overdose
Propofol-Related Infusion Syndrome (PRIS)

Diagnosis is based on a constellation of clinical suspicion and biochemical signs including:
Propofol-Related Infusion ... Syndrome (PRIS) ... #Syndrome #PRIS ... Diagnosis #Management #Pharmacology ... #Toxicity #Toxicology
Naloxone - Toxicology

Adult starting dose:
 - 0.4 mg IV/IM/IO/SQ for non-opioid dependent patients
 - 0.04 mg
Naloxone - Toxicology ... If an infusion is ... Naloxone #Narcan #Toxicology ... #Management #Pharmacology ... #Overdose
Therapeutic Drug Level Monitoring 
Carbamazepine - Sample immediately before next dose (trough) 
Clozapine - Sample immediately
at anytime if toxicity ... Theophylline - For i/v infusion ... - Continuous infusion ... Therapeutic #Ranges #Toxicology ... #Pharmacology #
Anti-IL6 Agents (Tocilizumab, Siltuximab) in COVID19

IL-6 activates T cells and macrophages, among other cell types (see
Anti-IL6 Agents ... in COVID19 IL ... Cytokine Activation Syndrome ... ALT) > 22% - Infusion ... Siltuximab #COVID19 #Pharmacology
Stages of Iron Toxicity

Iron overdose can cause an anion gap metabolic acidosis. Severe cases can lead
Stages of Iron Toxicity ... Iron overdose ... hrs Stage Ill ... #Stages #Iron #Toxicity ... #Toxicology #Diagnosis
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
Propofol infusion ... syndrome (PRIS) ... glycol (solvent) toxicity ... No pharmacologic ... (Haldol) - No pharmacologic
Phases of Colchicine Toxicity
 - Early Phase (0-24h) 
 - Multi-organ failure Phase (1-7 days)
of Colchicine Toxicity ... Respiratory Distress Syndrome ... #Colchicine #Toxicity ... #Toxicology #Phases ... #Pharmacology #