Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Antiarrhythmics - Vaughan Williams Classification
Class I (Ia, Ib, Ic) - Na+ Channel Blockade
 β€’ Slows depolarization
Vaughan Williams Classification ... AP cells β€’ Slows ... AP cells β€’ Slow ... VaughanWilliams #Classification ... #Classes #cardiology
Antiarrhythmics - Vaughan Williams Classification:
CLASS 1 - Sodium Channel Blockers:
 β€’ MOA: Block fast Na+ channels
Vaughan Williams Classification ... Action, ↑ EFR & AP ... Action, ↓ EFR & AP ... #Pharmacology #Classification ... #Classes #pathophysiology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Algorithm Before ... wasting from other causes ... suggests extra-renal causes ... differential #potassium #nephrology ... #low
Antiarrhythmics Pharmacology Summary
Cardiac Conduction Phases:
Phase 0 - Ventricular Depolarization:
 β€’ Na+ channels open leading to a
Vaughan Williams Classification ... Action, ↑ EFR & AP ... Action, ↓ EFR & AP ... #Pharmacology #Classification ... #Classes #pathophysiology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 β€’ Normal Acid-Base: Low intake
 β€’ Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... Normal Acid-Base: Low ... Differential #Diagnosis #Algorithm ... #causes #potassium ... #low #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Once pseudohypokalemia is ruled out, causes of hypokalemia can be
Causes of Hypokalemia ... is ruled out, causes ... filling of bucket (low ... #Causes #workup ... #nephrology
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
require urgent nephrology ... evaluation? ... : Hypovolemia, Low ... PROBLEM ~80% of AKI cases ... CONSIDER INTRINSIC CAUSES
Hyponatremia - Differential Diagnosis Algorithm
ADH Independent:
 β€’ Tea and Toast Syndrome, Beer Potomania - Low solute
Differential Diagnosis Algorithm ... Beer Potomania - Low ... or other losses ... Differential #Diagnosis #Algorithm ... #causes #nephrology
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
- Anorexia GI Losses ... Differential #Diagnosis #Low ... #Potassium #Table ... #Classification ... #Causes
Hypokalemia Differential Diagnosis Algorithm

Low intake 
β€’ poor oral intake 

Renal loss 
β€’ Medication 
β€’ Hypomagnesemia 
β€’
Differential Diagnosis Algorithm ... Low intake ... Differential #Diagnosis #Algorithm ... #Causes #Classification