Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Algorithm for Investigation ... of Abnormal Coagulation ... #Coagulation #Abnormal ... #APTT #Laboratory ... #Hematology #Diagnosis
Summary of Coagulation Deficiencies
Inherited:
 β€’ Hemophilia A - Deficiency of Factor VIII
 β€’ Hemophilia B -
Anticoagulant Medications ... ) β€’ Advanced Liver ... Alcohol, Viral hepatitis ... #comparison #diagnosis ... #hematology #deficiency
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 β€’ Infectious: Hepatitis C, A,
- Differential Diagnosis ... Toxic: Alcohol, Medication ... #Differential #Diagnosis ... Causes #Acute #algorithm ... #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (Β± cirrhosis)
Kidney Failure Coagulation ... Alcohol-Associated Hepatitis ... (DILI) Viral Hepatitis ... Failure #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury β†’ liver test abnormalities without evidence of liver
- Differential Diagnosis ... β€’ Infections: Hepatitis ... , HSV, VZV β€’ Medications ... #hepatology #algorithm ... Transaminitis #LFTs #hepatitis
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
and Acute Fatty Liver ... presents with coagulation ... pregnancy * Severe coagulation ... AFLP #obstetrics #hematology ... #diagnosis #table
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
presents with coagulation ... pregnancy * Severe coagulation ... Obstetrics #OBGyn #Hematology ... #Diagnosis #Comparison ... #Table
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... ) or metabolic liver ... Possible drug-induced liver ... Presence of atypical laboratory ... #Diagnosis #Hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
disease to acute liver ... hepatocellular pattern of liver ... Management - Strong indications ... Necrosis) If mild laboratory ... #Management #Hepatology
Autoimmune Hepatitis - Testing Algorithm
Individual Tests:
 β€’ F-Actin (Smooth Muscle) Antibody, IgG by ELISA with Reflex
Autoimmune Hepatitis ... - Testing Algorithm ... IgG by IFA β€’ Liver ... #Algorithm #diagnosis ... #hepatology