Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... cytopenias (usually anemia ... Allogeneic stem cell ... #Management #treatment ... #hematology #oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 β€’ Recurrent infections from neutropenia
 β€’ Mucosal bleeding from
: β€’ Recurrent infections ... Treatment: β€’ Consider ... stem cell transplant ... #diagnosis #management ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Hemophagocytic Lymphohistiocytosis ... Overwhelming clinical syndrome ... Low or absent NK cell ... #management #treatment ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 β€’ Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... Hemolytic uremic syndrome ... ) (e.g. lupus, CLL ... #hematology #anemia
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)β†’Activation of CD8 T cells (IFN-y) β†’ Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... Unknown cause Treatment ... Taar #HLH #Hemophagocytic ... #management #treatment ... #summary #rheumatology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 β€’ Acute infection
 β€’ Solid organ
- Differential Diagnosis ... malignancies β€’ Anemia ... Myelodysplastic syndrome ... myeloid leukemia (CML ... #Causes #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 β€’ Most common leukemia in adults
 β€’ Disorder of
Lymphocytic Leukemia (CLL ... 5) Symptoms of anemia ... uw_IMresidency #CLL ... Leukemia #oncology #hematology ... #management
Hemophagocytic Lymphohistiocytosis (HLH) Treatment
Primary HLH:
 - HLH-94 Protocol
    β€’ Dexamethasone
Hemophagocytic Lymphohistiocytosis ... (HLH) Treatment ... associated with infection ... EricsMedicalLectures/ #HLH #Hemophagocytic ... #management #hematology
Visceral Leishmaniasis - Diagnosis and Management Summary
Species: Leishmania donovani, Leishmania infantum, Leishmania chagasi
Where: South Asia, East
and Management ... and NO, Suppress induction ... β€’ Can cause Hemophagocytic ... Lymphohistiocytosis β€’ Anemia ... #management #treatment
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic complaints- anemia ... of the steroid treatment ... Treatment of GCA ... them, but urgent rheumatology ... #Management