Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief πŸ‡΅πŸ‡­ πŸ‡ΊπŸ‡Έ - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... to be present Treatment ... Guidelines): β€’ Anticoagulation ... Antiphospholipid #Syndrome ... #management #anticoagulation
Low-dose aspirin and low-molecular-weight heparin in lupus and Antiphospholipid Syndrome (APS) pregnancy

β€’ No previous history of
Antiphospholipid Syndrome ... gestation : Aspirin + preventive ... : Aspirin Β± preventive ... Antiphospholipid #Syndrome ... #Obstetrics #Anticoagulation
Behcet's Syndrome - Treatment
Ulcers:
 β€’ Treatment: Topical steroids
 β€’ Prevention: Colchicine
 β€’ Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Topical steroids β€’ Prevention ... immunosuppressive meds β€’ +/- Anticoagulation ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS
Venous Thrombosis - Arterial Thrombosis
INR Target
Duration
Recurrence

Dr. Laurent ARNAUD
Antiphospholipid Syndrome ... ) APS Venous Thrombosis ... Antiphospholipid #Syndrome ... #APS #management ... #hematology #treatment
2019 EULAR Recommendations - Obstetrics Management in (Antiphospholipid Syndrome) APS
Previous Thrombosis?
Previous Pregnancy Complications?

Dr. Laurent ARNAUD @Lupusreference

#obstetrics
Antiphospholipid Syndrome ... ) APS Previous ... #APS #management ... EULAR2019 #guidelines #rheumatology ... #obgyn #treatment
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Clarkson’s Disease - Capillary ... leak syndrome ... disease flares: β€’ Prevention ... Clarksons #Disease #Capillary ... #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 β€’ Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... have fever - ACS ... organ damage β€’ Treatment ... Low calcium β€’ Treatment ... diagnosis #management #hematology
Clotmaster Consensus 2019: Duration of Therapy for Venous Thromboembolic Disease
 β€’ Superficial Venous Thrombosis
 β€’ Upper
DVT or PE - Prevention ... post-thrombotic syndrome ... Bloodman #VTE #anticoagulation ... management #DVT #hematology ... #length #treatment
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 β†’ start cefepime Β± vancomycin (if
weakness, urinary retention ... stenting - Consider anticoagulation ... β†’ no immediate treatment ... after CRS) - Treatment ... AML (~20 %) and APL
Longterm Venous Thromboembolism Treatment Algorithm
Treat for 3 months and reassess
 β€’ Isolated distal DVT (without cancer)
Thromboembolism Treatment ... if D-dimer or APA ... Thromboembolism #Treatment ... Algorithm #management #hematology ... #anticoagulation