Dr. Gerald Diaz @GeraldMD
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Board Certified Internal Medicine Hospitalist, GrepMed Editor in Chief 🇵🇭 🇺🇸 - Sign up for an account to like, bookmark and upload images to contribute to our community platform. Follow us on IG: https://www.instagram.com/grepmed/ | Twitter: https://twitter.com/grepmeded/
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2019 EULAR recommendations for thrombosis in (Antiphospholipid Syndrome) APS
Venous Thrombosis - Arterial Thrombosis
INR Target
Duration
Recurrence

Dr. Laurent ARNAUD
Antiphospholipid Syndrome ... #APS #management ... #EULAR2019 #guidelines ... #rheumatology # ... hematology #treatment
2019 EULAR Recommendations - Obstetrics Management in (Antiphospholipid Syndrome) APS
Previous Thrombosis?
Previous Pregnancy Complications?

Dr. Laurent ARNAUD @Lupusreference

#obstetrics
) APS Previous ... #APS #management ... #EULAR2019 #guidelines ... #rheumatology # ... obgyn #treatment
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... to be present Treatment ... Guidelines): • Anticoagulation ... Antiphospholipid #Syndrome ... #management #anticoagulation
Low-dose aspirin and low-molecular-weight heparin in lupus and Antiphospholipid Syndrome (APS) pregnancy

• No previous history of
Antiphospholipid Syndrome ... gestation : Aspirin + preventive ... : Aspirin ± preventive ... Antiphospholipid #Syndrome ... #Obstetrics #Anticoagulation
Behcet's Syndrome - Treatment
Ulcers:
 • Treatment: Topical steroids
 • Prevention: Colchicine
 • Azathioprine for refractory disease
Arthritis:
Behcet's Syndrome ... Topical steroids • Prevention ... immunosuppressive meds • +/- Anticoagulation ... Behcets #disease #Syndrome ... #pharmacology #rheumatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
: - Neuro: AMS ... have fever - ACS ... organ damage • Treatment ... Low calcium • Treatment ... diagnosis #management #hematology
Clotmaster Consensus 2019: Duration of Therapy for Venous Thromboembolic Disease
 • Superficial Venous Thrombosis
 • Upper
DVT or PE - Prevention ... post-thrombotic syndrome ... Bloodman #VTE #anticoagulation ... management #DVT #hematology ... #length #treatment
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... edema, compartment syndrome ... disease flares: • Prevention ... Capillary #leak #syndrome ... #rheumatology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
weakness, urinary retention ... stenting - Consider anticoagulation ... → no immediate treatment ... after CRS) - Treatment ... AML (~20 %) and APL
Longterm Venous Thromboembolism Treatment Algorithm
Treat for 3 months and reassess
 • Isolated distal DVT (without cancer)
Thromboembolism Treatment ... if D-dimer or APA ... Thromboembolism #Treatment ... Algorithm #management #hematology ... #anticoagulation