Mithu Maheswaranathan, MD @MithuRheum
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Rheumatologist at Duke University Creator of Rheum OnePagers ➡ RheumOnePagers.com Twitter: @MithuRheum ➡ https://twitter.com/MithuRheum
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rheumatology differential antibodies ana antinuclear management patterns systemic aortitis associations autoantibodies cerebritis clinical cns crisis erythematosus lupus mimics msas myositis
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
erythematosus (SLE ... erythematosus (SLE ... erythematosus (SLE ... ANA #patterns #rheumatology ... #diagnosis #differential
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... TIF1y, MDA5 • Scleroderma ... #diagnosis #associations ... #table
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
erythematosus (SLE ... erythematosus (SLE ... erythematosus (SLE ... ANA #patterns #rheumatology ... #diagnosis #differential
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
Systemic Sclerosis (Scleroderma ... 3 Subtypes of Scleroderma ... Sclerosis sine scleroderma ... #SSc #rheumatology ... #diagnosis #signs
Scleroderma Mimics • Scleredema • Scleromyxedema (papular mucinosis) • Eosinophilic Fasciitis • Nephrogenic Systemic Fibrosis •
Scleroderma Mimics ... • Scleredema ... @MithuRheum #Scleroderma ... #Mimics #rheumatology ... #differential #diagnosis
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
TIF1y, NXP2, Mi-2, SAE ... MSAs #clinical #diagnosis ... #rheumatology # ... table
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... permeability Diagnosis ... Erythematosus #SLE ... CNS #neurology #rheumatology ... #cerebritis #diagnosis
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
- Differential Diagnosis ... erythematosus (SLE ... #Differential #Diagnosis ... #rheumatology
Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)
Scleroderma Renal ... Presentation of Scleroderma ... Biopsy to confirm diagnosis ... Renal #Crisis #rheumatology ... #nephrology #diagnosis
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