The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings

Predisposing Factors:
 - Immunocompromised, Diabetes,
 - Elderly, Female
Immunocompromised, Diabetes ... lower tract: As a complication ... Serratia #Upper #UrinaryTractInfection ... #UUTI #Pathophysiology
Diabetic Nephropathy: Pathogenesis
 - Metabolic Pathway
 - Hemodynamic Pathway

#Diabetic #Nephropathy #Diabetes #pathophysiology
Diabetic Nephropathy ... Hemodynamic Pathway #Diabetic ... #Nephropathy #Diabetes ... #pathophysiology
Lower Urinary Tract Infections: Complications
 - Infection damages the urinary tract epithelium causing fibroblast proliferation and
Tract Infections: Complications ... NH3) #Lower #UrinaryTractInfection ... #LUTI #Pathophysiology ... #Complications
Diabetic Retinopathy: Pathogenesis and clinical findings

Mild Non-proliferative DR
 • Outpouchings of the weakened capillary walls or
Diabetic Retinopathy ... Neovascularization #Diabetic ... #Retinopathy #Diabetes ... ophthalmology #diagnosis #complications ... #pathophysiology
Spondylosis - Pathogenesis and Complications

Vertebral disease that may compress the vertebral canal from all sides
Note: Do
Pathogenesis and Complications ... #Spondylosis #pathophysiology ... #msk #complications
Fecal Incontinence - Pathogenesis and Complications
Continence mechanisms are impaired
 • Local neuronal damage
 • External and
Pathogenesis and Complications ... Diabetes) • Altered ... Incontinence #geriatrics #pathophysiology
Falls: Pathogenesis and Complications
Poly-pharmacy
Disorders affecting movement and balance
 - Sensory deficits
 - Neuromuscular degeneration/Cerebrovascular disease
 -
Pathogenesis and Complications ... Geriatrics #Falls #pathophysiology ... #complications
Lower Urinary Tract Infection: Pathogenesis and Clinical Findings

- Predisposing Factors:  Immunocompromised state, diabetes, elderly, female
Immunocompromised state, diabetes ... rare) #Lower #UrinaryTractInfection ... #LUTI #Pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Signs/Symptoms/Complications ... Obesity -> Type 2 diabetes ... Syndrome #genetics #pathophysiology
Diabetic Foot: Pathogenesis and clinical findings
 • Polyol Pathway - Excess glucose enters Polyol pathway ->
Diabetic Foot: Pathogenesis ... neuropathy => Diabetic ... #DiabeticFoot #pathophysiology ... #complications ... #Diabetes