The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology symptoms peds dementia genetics psychiatry 21hydroxylasedeficiency 21ohd alzheimersdisease ankylosingspondylitis anorexianervosa bulimianervosa endocrinology falls lewybody msk orthopedics otitismedia pagetsdisease praderwilli
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
onto lateral hip Signs ... /Symptoms/Complications ... affected leg #FemoralHead ... #diagnosis #pathophysiology ... #signs #symptoms
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... Incr Skeletal fractures ... pathophysiology #peds #pediatrics
Falls: Pathogenesis and Complications Poly-pharmacy Disorders affecting movement and balance - Sensory deficits - Neuromuscular degeneration/Cerebrovascular disease -
Pathogenesis and Complications ... Lifestyle #Geriatrics ... pathophysiology #complications ... #diagnosis
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
chromosome 21) Signs ... / Symptoms / Complications ... pathophysiology #geriatrics ... #diagnosis #signs
Lewy Body Dementia: Pathogenesis and Clinical Findings Lewy Body Dementia is a sub-category of major or mild
a hierarchy of diagnostic ... (required for diagnosis ... function Core features ... pathophysiology #geriatrics ... #diagnosis
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
resolve by 72 hours Complications ... pathophysiology #diagnosis ... #symptoms #signs ... #peds #pediatrics
Ankylosing Spondylitis: Pathogenesis and Clinical findings • Pain in lumbar area and gluteal region: (Dull, insidious
column) • Late complication ... bamboo spine) -> Fracture ... pathophysiology #diagnosis ... #signs #symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... endocrinology #peds #pediatrics
Bulimia Nervosa: Signs and Symptoms Associated Psychological / Behavioural Features • Feelings of shame, guilt and embarrassment
Bulimia Nervosa: Signs ... / Behavioural Features ... Symptoms related to complications ... pathophysiology #diagnosis ... #signs #symptoms
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
Anorexia Nervosa: Complications ... increased risk of fracture ... Death - Cardiac complications ... pathophysiology #diagnosis ... #signs #symptoms
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