The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
startle reflex • Anxiety ... of trauma • Avoidance ... BehavioralDisorder #Pathophysiology
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings

Symptoms (included in DSM 5 criteria) - Present during
included in DSM 5 criteria ... partum onset) - Anxiety ... MoodDisorders #Diagnosis #Pathophysiology
Panic Disorder: Pathogenesis and clinical findings
Social Factors
 • Parenting and infant attachment
 • Childhood illness/abuse
 •
Experiential Avoidance ... • Avoidance of ... carrying anti-anxiety ... Anticipatory Anxiety ... BehavioralDisorder #Pathophysiology
Social Anxiety Disorder (SAD) - Pathophysiology 
Excessive fear of one or more social situations
 • Safety
Social Anxiety Disorder ... (SAD) - Pathophysiology ... Behaviors and Avoidance ... Panic Attacks, avoidance ... BehavioralDisorder #SAD #Pathophysiology
Pediatric Parasomnias and Nightmares: Pathogenesis and clinical findings

Parasomnias - Micro-arousal episodes during SWS ->
Intense activation of
system -> • Fear/anxiety ... Nightmares #Pediatrics #Peds ... #pathophysiology
Serotonin Syndrome: Pathogenesis and Clinical Findings
Serotonin Syndrome: Variable combination of mental status changes, autonomic instability, and
Mental Status - Anxiety ... Serotonin Toxicity Criteria ... Serotonin #Syndrome #Pathophysiology
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings
 - Must have >4 symptoms for >6 months,
develop mood and anxiety ... BehavioralDisorder #Pathophysiology ... signs #psychiatry #criteria