The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis pathophysiology psychiatry mnemonic personalitydisorder behavioraldisorder complications genetics gh growthhormone mooddisorders pediatrics peds pituitary syndrome urology 21hydroxylasedeficiency 21ohd adhd affectivedisorder
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Thyroid gland hyperplasia ... the etiology Signs ... /Symptoms: - Pretibial ... pathophysiology #endocin #endocrinology ... #symptoms #signs
Borderline Personality Disorder: Pathogenesis and Clinical Findings Behavioral Traits: • Unstable Relationships - Alternating extremes of idealization
experienced BPD ... the above with symptoms ... impairment #BPD ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Complications of Measles: Pathogenesis and Clinical Findings • ADEM -> Fever, headache, neck stiffness, BBD, mental
neck stiffness, BBD ... Complications #diagnosis #signs ... #symptoms #pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
congenital adrenal hyperplasia ... Signs/Symptoms/Complications ... pathophysiology #genetics #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Signs/Symptoms: ... Hyperthyroidism #endocrinology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome Signs ... /Symptoms/Complications ... : • Gonadal hypoplasia
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings Cognitive-Perceptual • Magical thinking - Belief in paranormal or
Personality Disorder (SPD ... familiarity SPD ... impairment #SPD ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
Major Depressive Disorder (MDD): Pathogenesis and Clinical Findings Symptoms (included in DSM 5 criteria) - Present during
Clinical Findings Symptoms ... included in DSM 5 criteria ... suicide Other Symptoms ... Pathophysiology #Signs ... #Symptoms #Psychiatry
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... /Symptoms: • GH ... #FeedbackLoop #endocrinology
Dependent Personality Disorder (DPD): Pathogenesis and Clinical Findings • Difficulties with Activities - Initiation Of projects
Personality Disorder (DPD ... themselves DPD ... care for self #DPD ... Diagnosis #Psychiatry #Criteria ... #Signs #Symptoms
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