The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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signs psychiatry msk acute behavioraldisorder bulimianervosa lupus retinopathy sle syndrome withdrawal adhd alcohol alzheimersdisease attentiondeficithyperactivedisorder caudaequina cecs centralretinalartery chronic chronicexertional
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
auto-reactive B and CD ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Musculoskeletal #Complications ... #pathophysiology ... #signs #symptoms ... #diagnosis
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
/ Complications ... Retinoblastoma #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
chromosome 21) Signs / Symptoms ... / Complications ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis ... #signs #symptoms
Chronic Hypertensive Retinopathy: Pathogenesis and clinical findings Ophthalmic Artery Hypertension Stage 1: Mild/vasoconstrictive • Acute and chronic vasospasm
hyalinization causes ... #Retinopathy #pathophysiology ... #ophthalmology ... #diagnosis #signs ... #symptoms #complications
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... spine Signs / Symptoms ... / Complications ... Syndrome #MSK #pathophysiology ... #diagnosis #symptoms
Acute Closed Angle Glaucoma: Pathogenesis and Clinical Findings OPHTHALMIC EMERGENCY: Early detection is essential, but most patients
• Significant cause ... most frequent cause ... / Complications ... ClosedAngle #Glaucoma #pathophysiology ... #ophthalmology
Diabetic Retinopathy: Pathogenesis and clinical findings Mild Non-proliferative DR • Outpouchings of the weakened capillary walls or
retinal ischemia causes ... Retinopathy #Diabetes #ophthalmology ... #diagnosis #complications ... #pathophysiology
Conduct Disorder (CD): Pathogenesis and clinical findings - Must have >3 symptoms present in the past
>18 years old, criteria ... weapon that can cause ... BehavioralDisorder #Pathophysiology ... #diagnosis #symptoms ... signs #psychiatry #criteria
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Clinical Findings Diagnostic ... Criteria - Fever ... /Complications: ... #Diagnosis #Pathophysiology ... #Signs #Symptoms
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