The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology complications ankylosingspondylitis avascularnecrosis benign bph centralretinalartery chondrocalcinosis cppd crao extraarticular hyperplasia injury kawasaki manifestations mastoiditis msk neurology occlusion ophthalmology
Paget’s Disease: Pathogenesis and Clinical Findings • Incr serum CTx - marker of bone resorption •
Paget’s Disease: ... formation #PagetsDisease ... pathophysiology #diagnosis ... #signs #symptoms
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Kawasaki Disease ... Clinical Findings Diagnostic ... Criteria - Fever ... hands & feet Signs ... #Criteria #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
Acute Spinal Cord ... Injury #Syndromes #diagnosis ... pathophysiology #signs ... #symptoms #msk ... #orthopedics #neurology
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
• Inflammatory Disease ... • Hematologic Disease ... trucking" • Acute ... ophthalmology #diagnosis ... #signs #symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Pathogenesis and Joint diseases ... • Non-specific Acute-phase ... Extra-articular signs ... pathophysiology #signs ... #symptoms #diagnosis
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
clinical findings Acute ... pathophysiology #signs ... #symptoms #diagnosis ... #otology
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
emptying - Voiding Symptoms ... Hydronephrosis, Acute ... Pathophysiology #Urology ... #Signs #Symptoms ... #Diagnosis
Chondrocalcinosis: Calcium Pyrophosphate Dihydrate (CPPD) Deposition Disease - Acute CPPD precipitation into the joint space ->
CPPD) Deposition Disease ... - Acute CPPD ... to crystals -> Acute ... #Signs #Symptoms ... Pathophysiology #Diagnosis
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: ... hearing loss #PagetsDisease ... pathophysiology #diagnosis ... #signs #symptoms
Avascular Necrosis: Pathogenesis and Clinical Findings • Physical Trauma (esp. to the scaphoid bone with damage
- Sickle-cell disease ... affected) - Acute ... hypolucency "Crescent sign ... pathophysiology #diagnosis ... #signs #symptoms
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