The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology signs symptoms acquired bonestrength caudaequina disorders erythematosus femur fractures incontinence lupus mania manic mixed musculoskeletal orthopedics osteoporosis pagetsdisease psychiatry
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Myopathy (Also caused ... Erythematosus #SLE #MSK ... Musculoskeletal #Complications ... signs #symptoms #diagnosis
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Equina Syndrome Causes ... Signs / Symptoms / Complications ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
fractures in elderly Causes ... Femur #Fractures #msk ... #orthopedics #diagnosis ... #differential # ... causes #pathophysiology
Mixed Urinary Incontinence: Pathogenesis and Clinical Findings Urgency Urinary Incontinence (UUI) -> Urinary leakage preceded by a
Incr PVR if a complication ... SUI or UUI not caused ... Signs #Symptoms #Urology ... #Diagnosis
Medical Conditions Causing Mania or Mania-Like Episodes: Pathogenesis • Bipolar Disorder -> Combination of individual, genetic,
circuitry -> Decreased Inhibitory ... Manic #Secondary #Causes ... #Differential # ... Diagnosis #Pathophysiology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... Abnormal Osteoclasts cause ... bone formation MSK ... pathophysiology #diagnosis ... signs #symptoms #complications
Acquired Disorders of Reduced Bone Strength: Pathogenesis • Hyperparathyroidism • Vitamin D deficiency • Malabsorption syndromes
Diabetes • Other causes ... • Aromatase inhibitors ... pathophysiology #differential ... #diagnosis #osteoporosis
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