The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Subtrochanteric Femur Fracture: Pathogenesis and clinical findings
 • Subtrochanteric region spans 5 cm distally from the
Subtrochanteric Femur Fracture ... in elderly Causes ... #msk #orthopedics ... #diagnosis #differential ... #causes #pathophysiology
Ankylosing Spondylitis: Pathogenesis and Clinical findings
 • Pain in lumbar area and gluteal region: (Dull, insidious
more constant as disease ... bamboo spine) -> Fracture ... minor trauma #AnkylosingSpondylitis ... pathophysiology #diagnosis
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Greater Trochanter Fracture ... pathophysiology #causes ... symptoms #signs #diagnosis ... #msk
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Acne • Coarse features ... Cardiovascular disease ... Overproduction #diagnosis
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings

 • Primary (Idiopathic): Unknown etiology, but associated
mellitus, thyroid disease ... , humeral head fracture ... a stroke that caused ... pathophysiology #diagnosis ... stages #staging #msk
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
sensory • Before diagnosis ... intervertebral disc disease ... MeralgiaParesthetica #MSK ... pathophysiology #differential ... #diagnosis #signs
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: ... Abnormal Osteoclasts cause ... bone formation MSK ... -> Pathologic fractures ... pathophysiology #diagnosis
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fracture Healing ... Stage (0-7d) • Fracture ... Fluoroquinolones - Causes ... #Orthopedics #msk ... pathophysiology #diagnosis
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
/ Behavioural Features ... Problems and Facial Features ... erosion and gum disease ... Sores, scars, calluses ... pathophysiology #diagnosis