The Calgary Guide to Understanding Disease @TheCalgaryGuide
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signs symptoms psychiatry msk complications behavioraldisorder differential immunology ophthalmology orthopedics pharmacology sideeffects allergic anxiety bulimianervosa criteria disorders etoh hypersensitivityreaction inhibitors
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... causes development ... of allergen-specific ... Allergic reaction ... #Immunology #pathophysiology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects • Serotonin Syndrome: - Autonomic Hyperactivity:
Selective Serotonin ... Side Effects • Serotonin ... Dizziness - Nausea ... #Inhibitors #Pathophysiology ... SideEffects #Psychiatry #Diagnosis
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine ... , Vomiting Serotonin ... gain Incr NE: Nausea ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... SideEffects #Psychiatry #Diagnosis
Allergic Rhinitis: Pathogenesis and clinical findings 1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Allergic Rhinitis ... Allergy Sensitization ... preformed (histamine, serotonin ... Tissue edema #Allergic ... Rhinitis #Rhinorrhea #pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings Definition: Small antigen-antibody complexes (produced from normal immune response to
self-antigens are the cause ... antigens are the cause ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Subjective Tinnitus: Pathogenesis and clinical findings Subjective Tinnitus - Perceived sound with no acoustic stimulus, heard only
refers to sound caused ... #Tinnitus #Causes ... #pathophysiology ... #differential #diagnosis
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
exposure to a likely allergen ... exposure to known allergen ... #Anaphylaxis #pathophysiology ... #immunology #diagnosis
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... cell surfaces causes ... leading to an allergic ... causes development ... Classification #Diagnosis
Septic Arthritis: Pathogenesis and clinical findings Notes: - Septic Arthritis is typically monoarticular & the knee is involved
involved in >50% of cases ... S.A. can also be caused ... SepticArthritis #pathophysiology ... #diagnosis
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect Examples: Valproate, Carbamazepine, Lamotrigine • Mild anticholinergic effect -> Drowsiness
constipation • Allergic ... Systemic effect -> Nausea ... #SideEffects #Pathophysiology
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