The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Alcohol Use Disorder: Pathogenesis and Clinical Findings

 • Tolerance (reduced sensitivity to effects of EtOH)
 •
Alcohol Use Disorder ... Recurrent use of alcohol ... to use EtOH • Withdrawal ... AlcoholUseDisorder #EtOH #Pathophysiology ... #Diagnosis #Signs
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
• Serotonin Syndrome ... Akathisia • SSRI Withdrawal ... Syndrome - ... Serotonin #Inhibitors #Pathophysiology ... SideEffects #Psychiatry #Diagnosis
Anticonvulsants as Mood Stabilizers: Mechanism and Side-effect
Examples: Valproate, Carbamazepine, Lamotrigine
 • Mild anticholinergic effect -> Drowsiness
Allergic reaction -> Benign ... Stevens-Johnson Syndrome ... decr intake -> Withdrawal ... #SideEffects #Pathophysiology
Opioid Withdrawal: Clinical Findings and Complications
Note: Opioid withdrawal can be extremely uncomfortable, but is rarely life-threatening
Opioid Withdrawal ... life-threatening (exceptions being ... of alcohol and/ ... #Opiate #Pathophysiology ... #Diagnosis #Signs
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Side Effects Withdrawal ... Vomiting Serotonin Syndrome ... SerotoninNorepinephrine #Inhibitors #Pathophysiology ... SideEffects #Psychiatry #Diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... • Central Cord Syndrome ... Posterior Cord Syndrome ... #diagnosis #pathophysiology ... #orthopedics #neurology
Refeeding Syndrome: Pathogenesis and clinical findings

Patients at Risk of Refeeding Syndrome:
 - Little or no nutritional
Refeeding Syndrome ... Risk of Refeeding Syndrome ... - History of alcohol ... #Refeeding #Syndrome ... #diagnosis #pathophysiology
Alcohol Withdrawal: Clinical Findings and Complications
The onset of alcohol withdrawal generally begins 6-24 hours after the
Alcohol Withdrawal ... Alcohol withdrawal ... #Alcohol #Withdrawal ... #Pathophysiology ... #Diagnosis #Signs
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings

Hormonal alterations (result of aging process)
    ->
Benign Prostatic ... stones #BPH #Benign ... Hyperplasia #Prostate #Pathophysiology ... #Urology #Signs ... #Symptoms #Diagnosis
Benzodiazepine (BZD) withdrawal: clinical findings and complications

 • Activation of ACC and OFC -> Feelings of
Benzodiazepine (BZD) withdrawal ... Asthma. or sense of being ... Benzodiazepine #BZD #withdrawal ... #pharmacology #pathophysiology ... #diagnosis #signs