The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Osteoarthritis (OA): X-ray features 
 - Joint space narrowing (least specific)
 - Subchondral Cysts (pockets of
Osteoarthritis (OA): X-ray ... (Thickening of bone ... under the areas of bone-bone ... Osteoarthritis #OA #Xray ... #radiology #diagnosis
Malignant Bone Tumors: Pathogenesis of X-ray appearance

 • Metastatic bone tumors (aka. cancerous cells from systemic
Malignant Bone Tumors ... Pathogenesis of X-ray ... tumors on X-ray ... BoneTumors #Malignant #Radiology ... #Diagnosis #XRay
Rheumatoid arthritis (RA): X-ray features
 • Soft tissue swelling (best seen by comparing left & right
arthritis (RA): X-ray ... Narrowing • Bony ... the articular bone ... #RA #HandXray #Diagnosis ... #Radiology #Clinical
Representative X-ray appearance of a primary benign bone tumor - Aneurysmal Bone Cyst 
 • Soft
Representative X-ray ... primary benign bone ... tumor - Aneurysmal Bone ... Narrowing • Bony ... #ShoulderXRay #Radiology
Representative X-ray appearance of a primary malignant bone tumor - Ewings Sarcoma
 • "Interrupted periosteal reaction
Representative X-ray ... primary malignant bone ... Moth-eaten", permeative bone ... transition between bone ... Ewings #Sarcoma #Radiology
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
3: Necrosis of bone ... destroying thin bony ... inner cortical bone ... signs #symptoms #diagnosis ... #otology
Benign Primary Bone Tumors: Pathogenesis of X-ray appearance
 • "Geographic" bone destruction
 • Lack of soft-tissue
Benign Primary Bone ... Pathogenesis of X-ray ... • "Geographic" bone ... Benign #BoneTumors #XRay ... #diagnosis #Radiology
Second Generation Antipsychotics: Mechanisms and Side Effects
(Atypical Anti-Psychotics) - Examples: Clozapine, Olanzapine, Quetiapine, Risperidone, Zotepine, Paliperidone,
action throughout body ... action throughout body ... SecondGeneration #Mechanisms #SideEffects ... #pharmacology #diagnosis
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings

Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
on axillary x-ray ... and underlying bone ... joint capsule or bone ... #Dislocation #Diagnosis
First Generation Anti-Psychotics: Mechanisms and Side Effects
Typical/Conventional Anti-Psychotics - Examples: Haloperidol, Chlorpromazine

ACh M1 antagonist - Block
ACh throughout body ... FirstGeneration #Mechanisms #SideEffects ... #pharmacology #diagnosis