The Calgary Guide to Understanding Disease @TheCalgaryGuide
549.5K 392 153
Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
Contributor Ranks
Latest Searches
24 results
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
follicle (others degenerate ... pathophysiology #comparison ... #endocrinology
Distinguishing between Inflammatory and Degenerative joint disease
Inflammatory Joint Disease
 • Swelling stimulates joint nociceptors -> Pain
Inflammatory and Degenerative ... ESR, RF, ANA) Degenerative ... #Inflammatory #Degenerative ... #Comparison #Versus
Falls: Pathogenesis and Complications
Poly-pharmacy
Disorders affecting movement and balance
 - Sensory deficits
 - Neuromuscular degeneration/Cerebrovascular disease
 -
Neuromuscular degeneration
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
• Large lumbar degenerative
Disc Herniations - Pathogenesis and Complications
• 90% of Lumbar disc herniations happen at L4/5 and L5/S1
•
C6/7 Aging ->Degeneration
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
pathophysiology #endocin #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Hyperthyroidism #endocrinology
Feedback Loop: Prolactin (PRL)
 • PRL levels exhibit diurnal, menstrual, and age-related variation
 • TRH has
#FeedbackLoop #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
#FeedbackLoop #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview
LH and FSH are required for follicular development and
#menstruation #endocrinology