The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis symptoms msk gh growthhormone pituitary 21hydroxylasedeficiency 21ohd caudaequina causes diabetes diabeticketoacidosis dka endocin excess feedbackloop gait genetics glftap
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... pathophysiology #endocin #endocrinology ... #symptoms #signs
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
• Large lumbar degenerative ... lumbar spine Signs ... diagnosis #symptoms #signs
Distinguishing between Inflammatory and Degenerative joint disease Inflammatory Joint Disease • Swelling stimulates joint nociceptors -> Pain
Inflammatory and Degenerative ... ESR, RF, ANA) Degenerative ... #Inflammatory #Degenerative ... #Comparison #Versus
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Signs/Symptoms: ... Hyperthyroidism #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates lipolysis Signs ... #FeedbackLoop #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
Overproduction #diagnosis #signs ... #symptoms #endocrinology
Trendelenburg Gait: Pathogenesis and clinical findings Skeletal Pathology of the Hip • Arthritis • Congenital hip dysplasia
around the hip • Degeneration ... causes #symptoms #signs
Keratoconus: Pathogenesis and Clinical Findings Genetics • Family history of keratoconus • Ehlers-Danlos syndrome • Down, Turner,
corneal thinning, degeneration ... > Keratoconus Signs ... Ring • Munson's sign ... • Rizutti's Sign
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles Note: Some charts show different relative levels of
follicle (others degenerate ... pathophysiology #comparison ... #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Signs / Symptoms ... #SideEffects #endocrinology
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