The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs symptoms orthopedics stages syndrome adhesivecapsulitis classification disruptors femoralhead frozenshoulder genetics grades grading healing pagetsdisease pediatrics peds pelvicring praderwilli
Classification of Pelvic Ring Fractures: Mechanisms, Clinical Features and Complications • Anterior Posterior Compression (APC) -
of Pelvic Ring Fractures ... bilateral rami fractures ... Grade 2 - Rami fracture ... #Orthopedics #MSK ... #pathophysiology
Femoral Head Fracture: Pathogenesis and clinical findings • Posterior hip dislocation -> Impaction force from femoral
Femoral Head Fracture ... • Non-union of fracture ... #FemoralHead #Fractures ... #msk #diagnosis ... #pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Signs/Symptoms/Complications ... Incr Skeletal fractures ... Obesity -> Type 2 diabetes ... Syndrome #genetics #pathophysiology
Cauda Equina Syndrome Causes: • Large lumbar degenerative disc herniation (central) • Severe lumbar spondylosis • Neoplasm
Signs / Symptoms / Complications ... pain (shooting, stabbing ... #CaudaEquina #Syndrome ... #MSK #pathophysiology
Adhesive Capsulitis (Frozen Shoulder) - Pathogenesis and Clinical Findings • Primary (Idiopathic): Unknown etiology, but associated
autoimmune disorders (diabetes ... , humeral head fracture ... FrozenShoulder #pathophysiology ... signs #stages #staging ... #msk
Fracture Healing (and disruptors of this process) Inflammatory Stage (0-7d) • Fracture disrupts local blood vessels ->
Fracture Healing ... Stage (0-7d) • Fracture ... chondrocytes at fracture ... #Orthopedics #msk ... #Staging #pathophysiology
Paget’s Disease: Complications Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation MSK
Paget’s Disease: Complications ... bone formation MSK ... -> Pathologic fractures ... PagetsDisease #pathophysiology ... signs #symptoms #complications
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