The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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clinical diagnosis malignant benign bonetumor labeled xray aneurysmalbonecyst complications diabetes diabeticketoacidosis ewings features feedbackloop findings gh growthhormone handxray legxray pituitary
Malignant Bone Tumors: Clinical Findings and Complications #Malignant #BoneTumors #Bony #Complications #pathophysiology
Malignant Bone Tumors ... #Malignant #BoneTumors ... #Bony #Complications ... #pathophysiology
Malignant Bone Tumors: Pathogenesis of X-ray appearance • Metastatic bone tumors (aka. cancerous cells from systemic
Malignant Bone Tumors ... • Metastatic bone ... tumors (aka. cancerous ... tumor #BoneTumors ... #Malignant #Radiology
Representative X-ray appearance of a primary benign bone tumor - Aneurysmal Bone Cyst • Soft
primary benign bone ... tumor - Aneurysmal Bone ... Narrowing • Bony ... #ShoulderXRay #Radiology ... Labeled #Benign #BoneTumor
Representative X-ray appearance of a primary malignant bone tumor - Ewings Sarcoma • "Interrupted periosteal reaction
primary malignant bone ... Moth-eaten", permeative bone ... transition between bone ... Ewings #Sarcoma #Radiology ... LegXRay #Malignant #BoneTumor
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... , body K+ is lost ... brain... thus, the body ... #pathophysiology ... #endocrinology
Rheumatoid arthritis (RA): X-ray features • Soft tissue swelling (best seen by comparing left & right
Narrowing • Bony ... the articular bone ... HandXray #Diagnosis #Radiology ... #Clinical #Pathophysiology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Incr IGF1 • Bone ... #FeedbackLoop #endocrinology ... #pathophysiology
Benign Primary Bone Tumors: Pathogenesis of X-ray appearance • "Geographic" bone destruction • Lack of soft-tissue
Benign Primary Bone ... • "Geographic" bone ... periosteum) #Benign #BoneTumors ... XRay #diagnosis #Radiology
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