The Calgary Guide to Understanding Disease @TheCalgaryGuide
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pathophysiology menstrualcycle ovariancycle diagnosis feedbackloop 21hydroxylasedeficiency 21ohd alzheimersdisease comparison constipation dementia erectile feedback follicularphase genetics gh glftap growthhormone hpoa hyperthyroidism
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
Pituitary Mass Effects ... Pituitary adenomas ... • For pituitary ... • Hypothalamic dysfunction ... #SideEffects #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview LH and FSH are required for follicular development and
- FSH from pituitary ... - LH from pituitary ... LH release from pituitary ... #menstruation #endocrinology
Menstrual Cycle Physiology: The Hypothalamic-Pituitary-Ovarian Axis Estrogen, when released: • Negatively feeds back on the hypothalamus and
The Hypothalamic-Pituitary-Ovarian ... hypothalamus and anterior pituitary ... hypothalamus and anterior pituitary ... HypothalamicPituitary #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained Early Follicular Phase (Days 0-5) • Granulosa cells
production by pituitary ... back on anterior pituitary ... production by pituitary ... feeds back on pituitary ... FollicularPhase #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
production by the pituitary ... Hyperthyroidism #endocrinology
Feedback Loop: Prolactin (PRL) • PRL levels exhibit diurnal, menstrual, and age-related variation • TRH has
#FeedbackLoop #endocrinology ... pathophysiology #pituitary
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
#FeedbackLoop #endocrinology ... pathophysiology #pituitary
Erectile Dysfunction: Pathogenesis Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... Pathogenesis Erectile Dysfunction ... Psychogenic Erectile Dysfunction ... and rigidity Endocrinologic ... Erectile Dysfunction
Alzheimer’s Disease: Pathogenesis and Clinical Findings Risk factor for Late Onset Alzheimer's (99% of cases): - Increasing
Executive planning dysfunction ... concentration • Motor dysfunction ... pathophysiology #geriatrics
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained Around Day 14, estrogen exerts sudden +++ positive feedback
on the anterior pituitary ... pathophysiology #Ovulation #endocrinology
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