The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Erectile Dysfunction: Pathogenesis

Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... Dysfunction - Persistent ... and rigidity Endocrinologic ... Erectile Dysfunction ... #Urology #Diagnosis
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
chromosome 21) Signs / Symptoms ... Executive planning dysfunction ... concentration • Motor dysfunction ... pathophysiology #geriatrics #diagnosis ... #signs #symptoms
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Diarrhea, Insomnia, Nausea ... Vertigo, Sexual Dysfunction ... gain Incr NE: Nausea ... SideEffects #Psychiatry #Diagnosis ... #Signs #Symptoms
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Equina Syndrome Causes ... spine Signs / Symptoms ... bladder/bowel dysfunction ... pathophysiology #diagnosis ... #symptoms #signs
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
For pituitary masses ... Signs / Symptoms ... Headaches • Nausea ... • Hypothalamic dysfunction ... #SideEffects #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
• Other rare causes ... Overproduction #diagnosis ... #signs #symptoms ... #endocrinology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Compensatory muscular dysfunction ... pathophysiology #causes ... #symptoms #signs ... #diagnosis #msk
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Abnormal Osteoclasts cause ... Skull expansion causes ... middle ear dysfunction ... pathophysiology #diagnosis ... #signs #symptoms
Anorexia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: concordance
abuse, familial dysfunction ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry #RiskFactors
Bulimia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: Some
CHARACTERISTICS Emotional Dysfunction ... states Cognitive Dysfunction ... pathophysiology #diagnosis ... #signs #symptoms ... #psychiatry #RiskFactors