The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
Graves’ Disease: ... pathophysiology #endocin ... #endocrinology ... #symptoms #signs ... #diagnosis
Low Ankle Sprain: Pathomechanics and Clinical Findings

Grading Ligament Sprains
l: Minimal ligament disruption, mild swelling & tenderness,
ligament substance leading ... ligament substance leading ... #Sports #MSK #orthopedics ... #Grading #Grades ... #Diagnosis #pathophysiology
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
severe Signs/Symptoms ... (uncommon) • Hearing ... abscess • High grade ... pathophysiology #symptoms ... #signs #diagnosis
Femoral Head Fracture: Pathogenesis and clinical findings
 • Posterior hip dislocation -> Impaction force from femoral
• Avulsion or shearing ... lateral hip Signs/Symptoms ... Fractures #msk #diagnosis ... pathophysiology #signs #symptoms ... #orthopedics
Fracture Healing (and disruptors of this process)
Inflammatory Stage (0-7d)
 • Fracture disrupts local blood vessels ->
Fracture Healing ... - Metabolic / Endocrine ... #Fracture #Healing ... #Stages #Orthopedics ... pathophysiology #diagnosis
Bulimia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: Some
female body as having ... in relation to eating ... purging, high rates ... pathophysiology #diagnosis ... #signs #symptoms
Anorexia Nervosa: Pathogenesis and Risk Factors
Biological Risk Factors
 • Gender: F > M
 • Genetics: concordance
Genetics: concordance rates ... female body as having ... pathophysiology #diagnosis ... #signs #symptoms
Anorexia Nervosa: Complications
CARDIAC ABNORMALITIES
 - Functional: Low BP, Sinus bradycardia, prolonged QT interval
 - Structural: Reduced
thrombocytopenia ENDOCRINE ... highest mortality rates ... pathophysiology #diagnosis ... #signs #symptoms