The Calgary Guide to Understanding Disease @TheCalgaryGuide
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signs symptoms msk gh orthopedics urology anorexianervosa anterior bakerscyst causes complications differential dislocation dysfunction endocin feedbackloop femur fractures gravesdisease hyperthyroidism
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... fraction • HTN #GrowthHormone ... #diagnosis #signs ... #symptoms #endocrinology ... #pathophysiology
Erectile Dysfunction: Pathogenesis Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... Pathogenesis Erectile ... and rigidity Endocrinologic ... #Dysfunction #Pathophysiology ... #Urology #Diagnosis
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipid • GH excess ... metabolic abn #GrowthHormone ... #FeedbackLoop #endocrinology ... #pathophysiology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
thyrotoxicosis due to excess ... hyperthyroidism due to excess ... Hyperthyroidism #endocrinology ... #pathophysiology
Priapism: Pathogenesis - Post-cavernosal venous occlusion -> Post-cavernosal venous drainage is mechanically obstructed e.g. sickle cell
detumescence (erection-ending ... Priapism Prolonged erection ... #Priapism #Pathophysiology ... #Urology #Diagnosis
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
GravesDisease #pathophysiology ... #endocin #endocrinology ... symptoms #signs #diagnosis
Subtrochanteric Femur Fracture: Pathogenesis and clinical findings • Subtrochanteric region spans 5 cm distally from the
Major trauma -> An excess ... #orthopedics #diagnosis ... differential #causes #pathophysiology
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
joint => Force exceeds ... #Dislocation #Diagnosis ... #orthopedics #pathophysiology
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
joint capsule exceeds ... RheumatoidArthritis #RA #pathophysiology ... signs #symptoms #diagnosis
Rickets and Osteomalacia: Pathogenesis and Clinical Findings • Calcification inhibitors (excess exposure to A1, Fluoride, etidronate)
Calcification inhibitors (excess ... #Osteomalacia #pathophysiology ... #diagnosis #signs
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