The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
GH excess prior ... GH excess after ... tolerance • Weight gain ... Overproduction #diagnosis ... signs #symptoms #endocrinology
Trendelenburg Gait: Pathogenesis and clinical findings

Skeletal Pathology of the Hip
 • Arthritis
 • Congenital hip dysplasia
Trendelenburg Gait ... Trendelenburg Gait ... Compensatory muscular dysfunction ... symptoms #signs #diagnosis ... #msk
Pituitary Mass Effects - Pathogenesis and Clinical Findings
 • Pituitary turnors are almost always a benign
following order; GH ... • Hypothalamic dysfunction ... #SideEffects #endocrinology
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Vertigo, Sexual Dysfunction ... , Weight gain Incr ... SideEffects #Psychiatry #Diagnosis
Erectile Dysfunction: Pathogenesis

Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
Erectile Dysfunction ... Pathogenesis Erectile Dysfunction ... and rigidity Endocrinologic ... Erectile Dysfunction ... Pathophysiology #Urology #Diagnosis
Achilles Tendon Rupture - Pathogenesis and clinical findings
 • The Achilles tendon is 15cm long in
rupture - Antalgic gait ... TendonRupture #diagnosis ... pathophysiology #msk
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Upper Extremity Dysfunction ... deficiencies -> Sphincter dysfunction ... Injury #Syndromes #diagnosis ... signs #symptoms #msk
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
sensory • Before diagnosis ... abnormalities (gait ... MeralgiaParesthetica #MSK ... #differential #diagnosis
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
bladder/bowel dysfunction ... CaudaEquina #Syndrome #MSK ... pathophysiology #diagnosis
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
bone formation MSK ... causes middle ear dysfunction ... pathophysiology #diagnosis