The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology psychiatry complications growthhormone mnemonic msk pituitary anorexianervosa anterior bakerscyst bulimianervosa criteria dislocation feedbackloop glftap gravesdisease hyperthyroidism macroadenoma masseffects narcissistic
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... #diagnosis #signs ... #symptoms #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... activates lipolysis Signs ... /Symptoms: • GH ... excess: - ... #FeedbackLoop #endocrinology
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
the etiology Signs ... pathophysiology #endocin ... #endocrinology ... #symptoms #signs ... #diagnosis
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
thyrotoxicosis due to excess ... hyperthyroidism due to excess ... Signs/Symptoms: ... Hyperthyroidism #endocrinology
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology
Anterior Shoulder Dislocation: Pathogenesis, clinical, and radiographic findings Trauma, Fall on, outstretched arm, Overhead throwing => Abduction
joint => Force exceeds ... #Dislocation #Diagnosis ... #signs #symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
joint capsule exceeds ... Extra-articular signs ... pathophysiology #signs ... #symptoms #diagnosis
Narcissistic Personality Disorder: Pathogenesis and Clinical Findings • Arrogant, Haughty Behaviors or Attitude - Often display
- Entitlement, Excess ... PersonalityDisorder #Diagnosis ... Psychiatry #Criteria #Signs ... #Symptoms #Mnemonic
Rickets and Osteomalacia: Pathogenesis and Clinical Findings • Calcification inhibitors (excess exposure to A1, Fluoride, etidronate)
Calcification inhibitors (excess ... pathophysiology #diagnosis ... #signs #symptoms
Anorexia Nervosa: Complications CARDIAC ABNORMALITIES - Functional: Low BP, Sinus bradycardia, prolonged QT interval - Structural: Reduced
thrombocytopenia ENDOCRINE ... - Lethargy or Excess ... pathophysiology #diagnosis ... #signs #symptoms
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