The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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diagnosis signs mnemonic psychiatry criteria pathophysiology growthhormone obsessivecompulsive ocpd pituitary 21hydroxylasedeficiency 21ohd amsuicide antisocial aspd avoidant avpd borderline bpd corrupt
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Growth Hormone (GH ... lipolysis Signs/Symptoms ... : • GH deficiency ... abn lipid • GH ... #FeedbackLoop #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
time of onset of GH ... GH excess prior ... GH excess after ... diagnosis #signs #symptoms ... #endocrinology
Obsessive-Compulsive Disorder (OCD): Pathogenesis and clinical findings Psychological Hypothesis • Cognitive behavioral model: Emotional disturbance arising from
ObsessiveCompulsive #PersonalityDisorder ... Psychiatry #Signs #Symptoms
Pituitary Mass Effects - Pathogenesis and Clinical Findings • Pituitary turnors are almost always a benign
following order; GH ... Signs / Symptoms ... #SideEffects #endocrinology
Borderline Personality Disorder: Pathogenesis and Clinical Findings Behavioral Traits: • Unstable Relationships - Alternating extremes of idealization
severe dissociative symptoms ... the above with symptoms ... BPD #Borderline #PersonalityDisorder ... Criteria #Signs #Symptoms
Graves’ Disease: Pathogenesis and Clinical Findings B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
etiology Signs/Symptoms ... pathophysiology #endocin #endocrinology ... #symptoms #signs
Primary Hyperthyroidism - Pathogenesis and Clinical Findings Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Signs/Symptoms: ... Hyperthyroidism #endocrinology
Schizotypal Personality Disorder (SPD): Pathogenesis and clinical findings Cognitive-Perceptual • Magical thinking - Belief in paranormal or
#Schizotypal #PersonalityDisorder ... Criteria #Signs #Symptoms
Dependent Personality Disorder (DPD): Pathogenesis and Clinical Findings • Difficulties with Activities - Initiation Of projects
DPD #Dependent #PersonalityDisorder ... Criteria #Signs #Symptoms
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
Signs/Symptoms/Complications ... pathophysiology #genetics #endocrinology
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