The Calgary Guide to Understanding Disease @TheCalgaryGuide
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menstrualcycle ovariancycle feedbackloop gh pituitary 21hydroxylasedeficiency comparison diagnosis excess follicularphase genetics hpoa hypothalamicpituitary lutealphase menstruation overproduction pediatrics peds prl prolactin
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained Around Day 14, estrogen exerts sudden +++ positive feedback
Ovarian Cycle – Ovulation ... sudden +++ positive feedback ... negative to positive feedback ... #OvarianCycle #pathophysiology ... #Ovulation #endocrinology
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth ... metabolic abn #GrowthHormone ... #FeedbackLoop #endocrinology ... #pathophysiology
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview LH and FSH are required for follicular development and
continued growth until ovulation ... theca cells • Ovulation ... forms following ovulation ... #OvarianCycle #pathophysiology ... #menstruation #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... fraction • HTN #GrowthHormone ... signs #symptoms #endocrinology ... #pathophysiology
Feedback Loop: Prolactin (PRL) • PRL levels exhibit diurnal, menstrual, and age-related variation • TRH has
Feedback Loop: Prolactin ... #FeedbackLoop #endocrinology ... #pathophysiology
Menstrual Cycle Physiology: The Hypothalamic-Pituitary-Ovarian Axis Estrogen, when released: • Negatively feeds back on the hypothalamus and
MenstrualCycle #pathophysiology ... HypothalamicPituitary #endocrinology ... #feedback
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
#21HydroxylaseDeficiency #21OHD ... #pathophysiology ... #genetics #endocrinology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles Note: Some charts show different relative levels of
Ovulation • ... See also "Ovulation ... • After ovulation ... #OvarianCycle #pathophysiology ... #comparison #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Luteal Phase Explained • The LH surge can be thought
slide) Besides ovulation ... #OvarianCycle #pathophysiology ... #LutealPhase #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Follicular Phase Explained Early Follicular Phase (Days 0-5) • Granulosa cells
preparing for ovulation ... #OvarianCycle #pathophysiology ... FollicularPhase #endocrinology
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