The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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feedbackloop gh menstrualcycle pituitary diabetes diagnosis excess hpoa hypothalamicpituitary ovariancycle overproduction ovulation prl prolactin signs symptoms
Feedback Loop: Growth Hormone (GH) Growth Hormone: • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
Feedback Loop: Growth ... metabolic abn #GrowthHormone ... #FeedbackLoop #endocrinology ... #pathophysiology
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Ketoacidosis (DKA ... Findings • Note: in DKA ... confusion coma #DiabeticKetoacidosis ... #DKA #pathophysiology ... #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained Around Day 14, estrogen exerts sudden +++ positive feedback
sudden +++ positive feedback ... negative to positive feedback ... #OvarianCycle #pathophysiology ... #Ovulation #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings • Acromegaly and gigantism share the same pathophysiology
share the same pathophysiology ... fraction • HTN #GrowthHormone ... signs #symptoms #endocrinology ... #pathophysiology
Feedback Loop: Prolactin (PRL) • PRL levels exhibit diurnal, menstrual, and age-related variation • TRH has
Feedback Loop: Prolactin ... #FeedbackLoop #endocrinology ... #pathophysiology
Menstrual Cycle Physiology: The Hypothalamic-Pituitary-Ovarian Axis Estrogen, when released: • Negatively feeds back on the hypothalamus and
MenstrualCycle #pathophysiology ... HypothalamicPituitary #endocrinology ... #feedback
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