The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Post-Traumatic Stress Disorder (PTSD)
Neurochemical abnormalities
 • Hyper-vigilance
 • Emotional hyper-arousal
 • Exaggerated startle reflex
 • Anxiety
StressDisorder #PTSD #BehavioralDisorder ... Pathophysiology #diagnosis #symptoms
Menstrual Cycle Physiology: Ovarian Cycle – Brief Overview
LH and FSH are required for follicular development and
MenstrualCycle #OvarianCycle ... #menstruation #endocrinology
Menstrual Cycle Physiology: Ovarian Cycle – Ovulation Explained

Around Day 14, estrogen exerts sudden +++ positive feedback
MenstrualCycle #OvarianCycle ... pathophysiology #Ovulation #endocrinology
Graves’ Disease: Pathogenesis and Clinical Findings
B & T lymphocyte mediated autoimmunity attack TSH receptor -> Continuous
etiology Signs/Symptoms ... pathophysiology #endocin #endocrinology ... #symptoms #signs
Attention Deficit Hyperactive Disorder (ADHD): Pathogenesis and clinical findings
 - For diagnosis, must have either 26
have either 26 symptoms ... Hyperactivity-Impulsivity or >6 symptoms ... 2 settings - Symptoms ... AttentionDeficitHyperactiveDisorder #ADHD #BehavioralDisorder ... Pathophysiology #diagnosis #symptoms
Menstrual Cycle Physiology: Ovarian Cycle – Luteal Phase Explained
 • The LH surge can be thought
MenstrualCycle #OvarianCycle ... #LutealPhase #endocrinology
Primary Hyperthyroidism - Pathogenesis and Clinical Findings

Note: Although rare, gestational diseases can lead to thyrotoxicosis due
Signs/Symptoms: ... Hyperthyroidism #endocrinology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipolysis Signs/Symptoms ... #FeedbackLoop #endocrinology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
diagnosis #signs #symptoms ... #endocrinology
Menstrual Cycle Physiology: Correlating the Ovarian and Uterine Cycles
Note: Some charts show different relative levels of
MenstrualCycle #OvarianCycle ... pathophysiology #comparison #endocrinology