The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis psychiatry symptoms signs pediatrics riskfactors 21hydroxylasedeficiency 21ohd anorexianervosa bulimianervosa criteria disorders dysfunction erectile nightmares odd oppositionaldefiant panicdisorder parasomnias pharmacology
Post-Traumatic Stress Disorder (PTSD) Neurochemical abnormalities • Hyper-vigilance • Emotional hyper-arousal • Exaggerated startle reflex • Anxiety
startle reflex • Anxiety ... StressDisorder #PTSD #BehavioralDisorder ... #Pathophysiology
Pathogenesis of Anxiety Disorders Anxiety Disorders: A maladaptive emotional state causing fear, worry, and excessive stress, characterized by:
Pathogenesis of Anxiety ... Disorders Anxiety ... reporting rates) • Genetics ... acid (GABA) #Anxiety ... #Disorders #Pathophysiology
Panic Disorder: Pathogenesis and clinical findings Social Factors • Parenting and infant attachment • Childhood illness/abuse •
Neurotic personality Genetics ... carrying anti-anxiety ... Anticipatory Anxiety ... #BehavioralDisorder ... #Pathophysiology
Prader-Willi Syndrome: Pathogenesis and clinical findings • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
PraderWilli #Syndrome #genetics ... #pathophysiology ... #peds #pediatrics
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
#21HydroxylaseDeficiency #21OHD #pathophysiology ... #genetics #endocrinology ... #peds #pediatrics
Pediatric Parasomnias and Nightmares: Pathogenesis and clinical findings Parasomnias - Micro-arousal episodes during SWS -> Intense activation of
system -> • Fear/anxiety ... Nightmares #Pediatrics #Peds ... #pathophysiology
Erectile Dysfunction: Pathogenesis Erectile Dysfunction - Persistent or recurrent inability to achieve an erection sufficient to achieve
erection present -> Anxiety ... and rigidity Endocrinologic ... #Dysfunction #Pathophysiology
Social Anxiety Disorder (SAD) - Pathophysiology Excessive fear of one or more social situations • Safety
Social Anxiety Disorder ... (SAD) - Pathophysiology ... reduce social anxiety ... SocialAnxiety #BehavioralDisorder ... #SAD #Pathophysiology
Oppositional Defiant Disorder (ODD): Pathogenesis and clinical findings - Must have >4 symptoms for >6 months,
develop mood and anxiety ... OppositionalDefiant #ODD #BehavioralDisorder ... #Pathophysiology
Anorexia Nervosa: Pathogenesis and Risk Factors Biological Risk Factors • Gender: F > M • Genetics: concordance
Gender: F > M • Genetics ... Temperament: childhood anxiety ... AnorexiaNervosa #pathophysiology
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