The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Acute onset of skin ... exposure to a likely allergen ... exposure to known allergen ... in the acute phase ... pathophysiology #immunology
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
Mastoiditis: Pathogenesis ... clinical findings Acute ... mucosa leads to inflammation ... abscesses #Mastoiditis ... pathophysiology #signs #symptoms
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
Acute Otitis Media ... Infection and inflammation ... severe Signs/Symptoms ... sensorineural is rare • Mastoiditis ... pathophysiology #symptoms
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
Acute Otitis Media ... bacterial. => Inflammation ... hearing loss, mastoiditis ... pathophysiology #diagnosis #symptoms
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
• Cardiac - Inflammation ... acute phase reactant ... - Ligamentous inflammation ... lung fibrosis #AnkylosingSpondylitis ... diagnosis #signs #symptoms
Cholesteatoma (of middle ear): Pathogenesis and clinical findings
 • Congenital trapping of keratinizing epithelium in middle
middle ear Signs / Symptoms ... Polyp secondary to inflammation ... • Acute otitis ... • Coalescent Mastoiditis ... pathophysiology #symptoms