The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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pathophysiology diagnosis signs ophthalmology lupus manifestations otitismedia sle urology achilles allergy anaphylaxis ankylosingspondylitis benign bph bulimianervosa centralretinalartery cholesteatoma chronic closedangle
Anaphylaxis: Signs and Symptoms Anaphylaxis: when any egg of three conditions is met: 1. Acute onset of skin/mucosal
Anaphylaxis: Signs and Symptoms ... Acute onset of skin ... in the acute phase ... / Complications ... pathophysiology #immunology
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
Acute Rheumatic ... Tissue injury and inflammation ... , Carditis #Acute ... diagnosis #signs #symptoms ... #complications
Acute Otitis Media: Complications Infection and inflammation of the middle ear - Prolonged obstruction of e. tube
Acute Otitis Media ... Infection and inflammation ... severe Signs/Symptoms ... Balance Problems #Acute ... pathophysiology #symptoms
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Vasculitis -> Acute ... Gastrointestinal #Complications ... pathophysiology #signs #symptoms
Retinoblastoma: Pathogenesis and clinical findings • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Retinoblastoma Signs / Symptoms ... / Complications ... reflex) • Orbital inflammation ... diagnosis #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
scaling that extend inflammation ... -> Incr local inflammation ... follicles due to inflammation ... diagnosis #signs #symptoms ... #complications
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
Acute Otitis Media ... bacterial. => Inflammation ... resolve by 72 hours Complications ... pathophysiology #diagnosis #symptoms
Achilles Tendon Rupture - Pathogenesis and clinical findings • The Achilles tendon is 15cm long in
warriors") • Acute ... etiology Signs/Symptoms ... /Complications: ... diagnosis #signs #symptoms
Mastoiditis: Pathogenesis and clinical findings Acute or Chronic Otitis Media -> Stage 1: Hyperemeia of the mastoid
clinical findings Acute ... mastoid air cells (inflammation ... mucosa leads to inflammation ... mastoid air cells (inflammation ... pathophysiology #signs #symptoms
Type I Hypersensitivity: Pathogenesis and clinical findings Definition: Production of lgE Antibodies that bind to harmless allergens
cells recruited Complications ... : • Acute Asthma ... HypersensitivityReaction #Allergy #Immunology
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