The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
Acute Otitis Media ... Infection and inflammation ... /Symptoms/Complications ... sensorineural is rare • Mastoiditis ... #signs #diagnosis
Anaphylaxis: Signs and Symptoms
Anaphylaxis: when any egg of three conditions is met:
1. Acute onset of skin/mucosal
Anaphylaxis: Signs ... Acute onset of skin ... in the acute phase ... Signs / Symptoms ... pathophysiology #immunology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
X-Linked Agammaglobulinemia ... Signs of immunodeficiency ... humoral immunity Signs ... /Symptoms/Findings ... pathophysiology #immunology
Mastoiditis: Pathogenesis and clinical findings

Acute or Chronic Otitis Media -> 
Stage 1: Hyperemeia of the mastoid
Mastoiditis: Pathogenesis ... clinical findings Acute ... abscesses #Mastoiditis ... pathophysiology #signs ... #symptoms #diagnosis
Orbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Chemosis: Edema of the bulbar conjunctiva
b. Panopthalmitis: inflammation of all
Orbital Cellulitis ... Panopthalmitis: inflammation ... Blindness #Orbital #Cellulitis ... ophthalmology #diagnosis #signs ... #symptoms
Periorbital Cellulitis: Pathogenesis and Clinical Findings
Definitions:
a. Dacryoadenitis: infection of the lacrimal glands
b. Conjunctivitis: inflammation of the
Periorbital Cellulitis ... Conjunctivitis: inflammation ... localized infection or inflammation ... ophthalmology #diagnosis #signs ... #symptoms
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
Acute Otitis Media ... bacterial. => Inflammation ... hearing loss, mastoiditis ... pathophysiology #diagnosis #symptoms ... #signs #peds #pediatrics
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... Tissue injury and inflammation ... , Carditis #Acute ... pathophysiology #diagnosis #signs ... #symptoms #complications
Cholesteatoma (of middle ear): Pathogenesis and clinical findings
 • Congenital trapping of keratinizing epithelium in middle
the middle ear Signs ... Polyp secondary to inflammation ... • Acute otitis ... • Coalescent Mastoiditis ... #signs #diagnosis
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features
 • RA affects 1% of population, women >
• Non-specific Acute-phase ... etc • Systemic inflammation ... Extra-articular signs ... pathophysiology #signs ... #symptoms #diagnosis