The Calgary Guide to Understanding Disease @TheCalgaryGuide
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Account created for The Calgary Guide to Understanding Disease - Linking pathophysiology to clinical presentation - http://calgaryguide.ucalgary.ca/
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Lupus (SLE): Mucocutaneous Manifestations

 • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Manifestations ... Phenomenon #Lupus #SLE ... #pathophysiology ... signs #symptoms #complications
Systemic Lupus Erythematosus: Gastrointestinal Manifestations
 - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... Erythematosus #SLE ... Gastrointestinal #Complications ... #pathophysiology
Acute Otitis Media: Complications
Infection and inflammation of the middle ear
 - Prolonged obstruction of e. tube
Otitis Media: Complications ... Infection and inflammation ... Problems #Acute #OtitisMedia ... #Complications ... #pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Erythematosus (SLE ... Musculoskeletal Manifestations ... Erythematosus #SLE ... Musculoskeletal #Complications ... #pathophysiology
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children)
Upper Respiratory Tract Infection: 
 - Bacterial: Streptococcus
. => Inflammation ... resolve by 72 hours Complications ... seizures, abscess (see ... mechanisms) #OtitisMedia ... #pathophysiology
Ankylosing Spondylitis: Extra-articular Manifestations
 • Ocular - Inflammation of the iris, the anterior part of the
Extra-articular Manifestations ... • Ocular - Inflammation ... Extraarticular #Manifestations ... #Complications ... #pathophysiology