The Calgary Guide to Understanding Disease @TheCalgaryGuide
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diagnosis pathophysiology signs complications lupus erythematosus extraarticular ra rheumatoidarthritis systemic ankylosingspondylitis benign bph centralretinalartery crao gastrointestinal msk mucocutaneous musculoskeletal occlusion
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
Lupus (SLE): Mucocutaneous ... Manifestations ... Phenomenon #Lupus #SLE ... Mucocutaneous #Manifestations ... diagnosis #signs #symptoms
Systemic Lupus Erythematosus: Gastrointestinal Manifestations - Thrombosis of vessels in the pancreas, Vasculitis -> Acute Pancreatitis
Gastrointestinal Manifestations ... Erythematosus #SLE ... pathophysiology #signs #symptoms
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... Musculoskeletal Manifestations ... Erythematosus #SLE ... pathophysiology #signs #symptoms
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
Extra-articular manifestations ... Skin: • Inflammation ... Eyes: • Globe inflammation ... on CXR • RA inflammation ... pathophysiology #signs #symptoms
Benign Prostatic Hyperplasia: Pathogenesis and Clinical Findings Hormonal alterations (result of aging process) ->
Benign Prostatic Hyperplasia ... FGF-related proteins) Inflammation ... granulocytes) -> Prostate Inflammation ... Benign #Prostatic #Hyperplasia ... Urology #Signs #Symptoms
Acute Otitis Media: Pathogenesis and Clinical Findings (in Children) Upper Respiratory Tract Infection: - Bacterial: Streptococcus
. => Inflammation ... seizures, abscess (see ... pathophysiology #diagnosis #symptoms
Rheumatoid arthritis (RA): Pathogenesis and Joint diseases features • RA affects 1% of population, women >
Extra-articular manifestations ... etc • Systemic inflammation ... pathophysiology #signs #symptoms
Central Retinal Artery Occlusion: Pathogenesis and clinical findings • Inflammatory Disease: (i.e. GCA, SLE, GPA) ->
GCA, SLE, GPA) - ... viscosity and inflammation ... diagnosis #signs #symptoms
Ankylosing Spondylitis: Extra-articular Manifestations • Ocular - Inflammation of the iris, the anterior part of the
Extra-articular Manifestations ... • Ocular - Inflammation ... • Cardiac - Inflammation ... Extraarticular #Manifestations ... diagnosis #signs #symptoms
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